The molecular adsorbent recycling system (MARS) and transmembrane transport of albumin-bound toxins
نویسندگان
چکیده
منابع مشابه
Molecular adsorbent recirculating system (MARS).
INTRODUCTION Molecular adsorbent recirculating system (MARS) for albumin liver dialysis has been used as a bridge to liver transplantation in patients with fulminant hepatic failure (FHF). This review examines the available data on its clinical use, its technical aspects and present gaps in knowledge. METHODS Peer-reviewed journals and monographs on the subject were covered. RESULTS FHF is ...
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Acute, acute-on-chronic and chronic liver diseases are major health issues worldwide, and most cases end with the need for liver transplantation. Up to 90% of the patients die waiting for an organ to be transplanted. Hepatic encephalopathy is a common neuropsychiatric syndrome that usually accompanies liver failure and impacts greatly on the quality of life. The molecular adsorbent recirculatin...
متن کاملThe molecular adsorbents recycling system as a liver support system based on albumin dialysis: a summary of preclinical investigations, prospective, randomized, controlled clinical trial, and clinical experience from 19 centers.
Artificial liver support aims to prolong survival time of patients with liver failure by detoxification. Albumin as a molecular adsorbent in dialysis solution is capable of attracting even tightly albumin-bound toxins from blood into the dialysate if a specific dialysis membrane is used and if the albumin's binding sites are on-line-purified by a sorbent/dialysis-based recycling system (i.e., m...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2005
ISSN: 1527-6465,1527-6473
DOI: 10.1002/lt.20450